2021 · Week 1 · 2021-09-12
San Francisco 49ers win.
| SF | DET | |
|---|---|---|
| Final score | 41 | 33 |
| Total yards | 442 | 430 |
| Passing yards | 311 | 314 |
| Rushing yards | 131 | 116 |
| First downs | 21 | 31 |
| 3rd down | 3-9 | 4-15 |
| 4th down | 0-0 | 2-5 |
| Total plays | 55 | 84 |
| Yards / play | 8.0 | 5.1 |
| Comp / att | 18/26 | 38/57 |
| Yards / pass | 11.5 | 5.2 |
| Rush attempts | 28 | 24 |
| Yards / rush | 4.7 | 4.8 |
| Red zone (made-att) | 2-2 | 3-3 |
| Turnovers | 2 | 1 |
| Interceptions | 0 | 1 |
| Fumbles lost | 2 | 0 |
| Sacks-yds | 1-8 | 3-24 |
| Penalties-yds | 7-79 | 5-45 |
| Drives | 12 | 14 |
| Possession | 26:33 | 33:27 |
