2021 · Week 4 · 2021-10-03
Buffalo Bills win.
| HOU | BUF | |
|---|---|---|
| Final score | 0 | 40 |
| Total yards | 109 | 450 |
| Passing yards | 61 | 251 |
| Rushing yards | 48 | 199 |
| First downs | 6 | 26 |
| 3rd down | 1-9 | 5-12 |
| 4th down | 1-2 | 1-2 |
| Total plays | 42 | 72 |
| Yards / play | 2.6 | 6.2 |
| Comp / att | 11/21 | 21/31 |
| Yards / pass | 2.5 | 7.8 |
| Rush attempts | 18 | 40 |
| Yards / rush | 2.7 | 5.0 |
| Red zone (made-att) | 0-1 | 3-7 |
| Turnovers | 5 | 1 |
| Interceptions | 4 | 1 |
| Fumbles lost | 1 | 0 |
| Sacks-yds | 3-26 | 1-5 |
| Penalties-yds | 10-100 | 3-30 |
| Drives | 12 | 12 |
| Possession | 21:45 | 38:15 |
