2021 · Week 11 · 2021-11-21
Indianapolis Colts win.
| IND | BUF | |
|---|---|---|
| Final score | 41 | 15 |
| Total yards | 370 | 311 |
| Passing yards | 106 | 220 |
| Rushing yards | 264 | 91 |
| First downs | 28 | 19 |
| 3rd down | 8-12 | 5-10 |
| 4th down | 0-1 | 0-0 |
| Total plays | 66 | 54 |
| Yards / play | 5.6 | 5.8 |
| Comp / att | 11/20 | 24/40 |
| Yards / pass | 5.3 | 5.4 |
| Rush attempts | 46 | 13 |
| Yards / rush | 5.7 | 7.0 |
| Red zone (made-att) | 4-6 | 2-2 |
| Turnovers | 0 | 4 |
| Interceptions | 0 | 3 |
| Fumbles lost | 0 | 1 |
| Sacks-yds | 0-0 | 1-8 |
| Penalties-yds | 3-30 | 7-56 |
| Drives | 9 | 10 |
| Possession | 37:47 | 22:13 |
